Ever seen the pitch by Dr Steven Sisskind-
Basic Medical Fact Number 1: Low Levels of Adiponectin
What is Adiponectin and Why Havenâ€™t You Heard of it?
Adiponectin is literally the hormone that tells your body to burn fat for fuel. It is now well established that the more of this super hormone you have circulating in your bloodstream, the more fat you burn.
Low levels of adiponectin are associated with higher levels of obesity. And elevated levels of adiponectin are not only associated with increased fat catabolism (i.e., fat burning), but also increased insulin sensitivity.
Additionally, adiponectin helps reduce insulin resistance. We will get to this later, but you need to know that insulin resistance is responsible for most blood sugar issues and something that makes it virtually impossible to lose weight even when following a low calorie diet.
The frustrating thing about adiponectin is that the more fat you have, the lower your adiponectin levels â€“ which is why LOSING fat is so difficult at the beginning.
It turns out that one of the best ways to increase adiponectin is to reduce the levels of one of the insidious hormones I will talk about later.
Basic Medical Fact Number 2: High Ghrelin Levels You might have heard of ghrelin, but if not it is something you need to know about. Ghrelin is
known as the â€œHunger Hormone.â€ Basically the more ghrelin you have in your system, the hungrier you are.
So if you find yourself fighting cravings and canâ€™t seem to stay away from the fridge after dinner,
it is probably due to elevated ghrelin levelsâ€¦
Ghrelin increases food intake and increases fat mass by an action exerted at the level of the hypothalamus in the brain.
Even worse, ghrelin activates the reward link in your brain for things like sweet, fatty foods, and even alcohol and cigarettesâ€¦
You can see why losing fat is almost impossible with elevated levels of ghrelin! And it turns out that the insidious hormones Iâ€™ll discuss below can also cause elevated ghrelin.
Basic Medical Fact Number 3: Insulin Resistance
If you are overweight, there is a good chance you are experiencing some level of insulin resistance. What this means is that your natural hormone insulin becomes less effective at lowering your blood sugars.
Your muscle cells require insulin to absorb glucose (sugars), but when these cells fail to respond adequately to circulating insulinâ€¦ blood sugars rise. Also, the liver is supposed to reduce its output of glucose in the presence of insulin, but with insulin resistance this also does not happen.
The net effect is that instead of pulling sugars into muscles for energy or burning sugar for energy, most of the carbohydrates you consume get stored as fat. You have probably heard about this at one level or another.
However, you probably have not heard that insulin resistance is also caused by one of the two â€œbadâ€ fat hormones I will get to later.
Basic Medical Fact Number 4: Cortisol
You might have heard about the fat â€“ stress connectionâ€¦ not only has stress been documented to increase cravings for sweet, fatty and salty foods, it also leads to increased cortisol production â€“ which leads directly to belly fat.
Cortisol also breaks down muscle for energy, which is NOT a good way to lose weight! Excess cortisol in your system leads to a slower metabolism, muscle loss, and fat accumulation in unsightly parts of your body like your abdomen and under your arms.
Many people who are overweight â€“ most notably those with fat in the belly, and high blood sugar or high blood pressure â€“ have elevated cortisol levels. This creates a vicious cycle: too much cortisol makes you gain weight. Being overweight makes it hard to produce adiponectin.
Which then makes you gain even more weight!
Like the other three medical facts above, excess cortisol is at its root caused by two hormones
that can simply wreck your metabolism.
Sorry to leave you hanging for so long, but I thought it was important to show you how many metabolic pathways these two insidious hormones can disruptâ€¦
One thing you may be familiar with that both of these hormones cause, besides obesity, is inflammation. Aches and pains are not all caused by injuries and overexertion.
A large percentage of chronic pain is actually caused by your hormones. If you are overweight, you might be experiencing stiffness, muscle soreness, and fatigueâ€¦ not because you are old or have old injuries.
But rather it might be because of a hormonal imbalanceâ€¦ of the two insidious hormones Tumor Necrosis Factor-Alpha (TNF-Î±) and Interleukin-6 IL-6 (IL6).
Both of these hormones have benefits inside the body â€“ mainly in fighting infections and elevating your immune system when it needs to go into battle. However, these hormones can also be toxicâ€¦ leading to obesity if not kept in check.
What Scientists Recently Discoveredâ€¦ The Leptin Connection... (more)
Unfortunately the source is just a commercial, but it says the right things. Dr Sisskind is pimping a supplement called Real Dose The pitch is that it accounts for the 4 things above, it is supported by double-blind studies, and they sell the same thing that was actually tested on humans-hence the brand name Real Dose.
Much of this we already know to be valid. Getting enough sleep, keeping stress, cortisol and insulin under control work. His diet advice includes avoiding simple sugars and high fat meat, eating your veggies, greek yogurt, and some other things that sound familiar like omega 3 fishoil and vitamin D and protein for breakfast.
I'm curious if you ever ran across this, or if anyone else has an opinion.