11-05-2008, 09:25 PM
Um maybe they did better partially because they were not eating carbs!
Quote:New Drug Prevents Weight Gain In Mice
SRT1720 for your pet mouse that refuses to stop eating junk food.
A potential longevity-enhancing drug has passed its final animal testing challenge, pushing closer to reality the dream of all-purpose drugs against diseases of aging.
Mice given the new drug, called SRT1720, gorged on high-fat food for four months without gaining weight or developing diabetes, and ran twice as far on a treadmill as their control-group counterparts. Similar drugs are expected to follow down the pipeline.
SRT1720 targets the gene SIRT1 also targeted by resveratrol while being far more potent.
The drug's side effects aren't yet apparent, but resveratrol has proven safe in animals and — anecdotally, at least — in humans. Since SRT1720 works at doses 1000 times lower than resveratrol, said Lambert, it should prove even safer if effective.
